Publications
Molitoris KH, Balu AR, Huang M, Baht GS. The impact of age and sex on the inflammatory response during bone fracture healing, JBMR Plus. May 2024.
Molitoris KH, Balu AR, Huang M, Baht GS. The impact of age and sex on the inflammatory response during bone fracture healing, JBMR Plus. May 2024.
Bareja A, Lee DE, Ho T, Waitt G, McKay LH, Hannou SA, Orenduff MC, McGreevy KM, Binder A, Ryan CP, Soderblom EJ, Belsky DW, Ferrucci L, Das JK, Banskota N, Kraus VB, Huebner JL, Kraus WE, Huffman KM, Baht GS, Horvath S, Parmer RJ, Miles LA, White JP. Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT. Cell Rep. 2024 Mar 4;43(3):113881.
Bareja A, Lee DE, Ho T, Waitt G, McKay LH, Hannou SA, Orenduff MC, McGreevy KM, Binder A, Ryan CP, Soderblom EJ, Belsky DW, Ferrucci L, Das JK, Banskota N, Kraus VB, Huebner JL, Kraus WE, Huffman KM, Baht GS, Horvath S, Parmer RJ, Miles LA, White JP. Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT. Cell Rep. 2024 Mar 4;43(3):113881.
Wu PY, Caceres AI, Chen J, Sokoloff J, Huang M, Baht GS, Nackley AG, Jordt SE, Terrando N. Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice. Pain. 2024 Feb 27.
Wu PY, Caceres AI, Chen J, Sokoloff J, Huang M, Baht GS, Nackley AG, Jordt SE, Terrando N. Vagus nerve stimulation rescues persistent pain following orthopedic surgery in adult mice. Pain. 2024 Feb 27.
B. Zhang, D. Lee, A. Trapp, A. Tyshkovskiy, A. Lu, A. Bareja, C. Kerepesi, L. McKay, A.V. Shindyapina, S. Dmitriev, G.S. Baht , S. Horvath , V. Gladyshev, J.P. White. Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation. Nat Aging. 2023 Jul 27.
B. Zhang, D. Lee, A. Trapp, A. Tyshkovskiy, A. Lu, A. Bareja, C. Kerepesi, L. McKay, A.V. Shindyapina, S. Dmitriev, G.S. Baht , S. Horvath , V. Gladyshev, J.P. White. Multi-omic rejuvenation and lifespan extension upon exposure to youthful circulation. Nat Aging. 2023 Jul 27.
Baht GS, Grol MW. Editorial: The immune system and inflammation in musculoskeletal health, aging, and disease. Front Immunol. 2023 May 18;14:1218118. doi: 10.3389/fimmu.2023.1218118.
Baht GS, Grol MW. Editorial: The immune system and inflammation in musculoskeletal health, aging, and disease. Front Immunol. 2023 May 18;14:1218118. doi: 10.3389/fimmu.2023.1218118.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Biological age is increased by stress and restored upon recovery. Cell Metab. 2023 Apr 4.
Poganik JR, Zhang B, Baht GS, Tyshkovskiy A, Deik A, Kerepesi C, Yim SH, Lu AT, Haghani A, Gong T, Hedman AM, Andolf E, Pershagen G, Almqvist C, Clish CB, Horvath S, White JP, Gladyshev VN. Biological age is increased by stress and restored upon recovery. Cell Metab. 2023 Apr 4.
Lee DE, McKay LK, Bareja A, Li Y, Khodabukus A, Bursac N, Taylor GA, Baht GS, White JP. Meteorin-like is an injectable peptide that can enhance regeneration in aged muscle through immune-driven fibro/adipogenic progenitor signaling. Nat Commun. 2022 Dec 9;13(1):7613.
Lee DE, McKay LK, Bareja A, Li Y, Khodabukus A, Bursac N, Taylor GA, Baht GS, White JP. Meteorin-like is an injectable peptide that can enhance regeneration in aged muscle through immune-driven fibro/adipogenic progenitor signaling. Nat Commun. 2022 Dec 9;13(1):7613.
Yan R, Cigliola V, Oonk KA, Petrover Z, DeLuca S, Wolfson DW, Vekstein A, Mendiola MA, Devlin G, Bishawi M, Gemberling MP, Sinha T, Sargent MA, York AJ, Shakked A, DeBenedittis P, Wendell DC, Ou J, Kang J, Goldman JA, Baht GS, Karra R, Williams AR, Bowles DE, Asokan A, Tzahor E, Gersbach CA, Molkentin JD, Bursac N, Black BL, Poss KD. An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair. Cell Stem Cell. 2022 Dec 6:S1934-5909(22)00459-3.
Yan R, Cigliola V, Oonk KA, Petrover Z, DeLuca S, Wolfson DW, Vekstein A, Mendiola MA, Devlin G, Bishawi M, Gemberling MP, Sinha T, Sargent MA, York AJ, Shakked A, DeBenedittis P, Wendell DC, Ou J, Kang J, Goldman JA, Baht GS, Karra R, Williams AR, Bowles DE, Asokan A, Tzahor E, Gersbach CA, Molkentin JD, Bursac N, Black BL, Poss KD. An enhancer-based gene-therapy strategy for spatiotemporal control of cargoes during tissue repair. Cell Stem Cell. 2022 Dec 6:S1934-5909(22)00459-3.
X. Zhang, G.S. Baht, R. Huang, Y. Chen, K.H. Molitoris, S.E. Miller, V.B. Kraus. Rejuvenation of neutrophils and their extracellular vesicles is associated with enhanced aged fracture healing. Aging Cell. (doi: 10.1111/acel.13651).
X. Zhang, G.S. Baht, R. Huang, Y. Chen, K.H. Molitoris, S.E. Miller, V.B. Kraus. Rejuvenation of neutrophils and their extracellular vesicles is associated with enhanced aged fracture healing. Aging Cell. (doi: 10.1111/acel.13651).
R. Huang, A.R. Balu, K.H. Molitoris, J.P. White, A.G. Robling, U.M. Ayturk, G.S. Baht. The role of Meteorin-like in skeletal development and bone fracture healing. J Orthop Res. (doi: 10.1002/jor.25286).
R. Huang, A.R. Balu, K.H. Molitoris, J.P. White, A.G. Robling, U.M. Ayturk, G.S. Baht. The role of Meteorin-like in skeletal development and bone fracture healing. J Orthop Res. (doi: 10.1002/jor.25286).
B. A. Alman and G.S. Baht. Parabiosis: Assessing the Effects of Circulating Cells and Factors on the Skeleton. Methods in Molecular Biology: Skeletal Development and Repair. 2021. 2230:105–13.
B. A. Alman and G.S. Baht. Parabiosis: Assessing the Effects of Circulating Cells and Factors on the Skeleton. Methods in Molecular Biology: Skeletal Development and Repair. 2021. 2230:105–13.
R. Huang, L. Vi, X. Zong. G.S. Baht. Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration. FASEB J. 2020. 34(10): 13521-13532 .
R. Huang, L. Vi, X. Zong. G.S. Baht. Maresin 1 resolves aged-associated macrophage inflammation to improve bone regeneration. FASEB J. 2020. 34(10): 13521-13532 .
G.S. Baht, A. Bareja, D.E. Lee, R.R. Rao, R. Huang, J.L. Huebner, D.B. Bartlett, C.R. Hart, J.R. Gibson, I.R. Lanza, V.B. Kraus, S.G. Gregory, B.M. Spiegelman, and J.P. White. Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism. Nature Metabolism. 2020. 2: 278-289.
G.S. Baht, A. Bareja, D.E. Lee, R.R. Rao, R. Huang, J.L. Huebner, D.B. Bartlett, C.R. Hart, J.R. Gibson, I.R. Lanza, V.B. Kraus, S.G. Gregory, B.M. Spiegelman, and J.P. White. Meteorin-like facilitates skeletal muscle repair through a Stat3/IGF-1 mechanism. Nature Metabolism. 2020. 2: 278-289.
Zeng Y, Shih YV, Baht GS, Varghese S. In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing. Adv Mater. 32(8): 2020.
Zeng Y, Shih YV, Baht GS, Varghese S. In Vivo Sequestration of Innate Small Molecules to Promote Bone Healing. Adv Mater. 32(8): 2020.
Miller-Rhodes P, Kong C, Baht GS, Saminathan P, Rodriguiz RM, Wetsel WC, Gelbard HA, Terrando N. The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders. J Neuroinflammation. 16(1): 2019,193.
Miller-Rhodes P, Kong C, Baht GS, Saminathan P, Rodriguiz RM, Wetsel WC, Gelbard HA, Terrando N. The broad spectrum mixed-lineage kinase 3 inhibitor URMC-099 prevents acute microgliosis and cognitive decline in a mouse model of perioperative neurocognitive disorders. J Neuroinflammation. 16(1): 2019,193.
R. Huang, X. Zong, P. Nadesan, J.L. Huebner, V.B. Kraus. J.P. White, P.J. White, and G.S. Baht. Lowering circulating apolipoprotein E levels improves aged bone fracture healing. JCI Insight. 4(18): 2019, 1-13.
R. Huang, X. Zong, P. Nadesan, J.L. Huebner, V.B. Kraus. J.P. White, P.J. White, and G.S. Baht. Lowering circulating apolipoprotein E levels improves aged bone fracture healing. JCI Insight. 4(18): 2019, 1-13.
L. Vi*, G.S. Baht*, E.J. Soderblom, H. Whetstone, Q. Wei, B. Furman, V. Puviindran, M. Foster, R. Poon, J.P. White, Y. Yahara, A. Ng, T. Barrientos, M. Grynpas, M.A. Mosely, B.A. Alman. Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice. Nature Communications. 9: 2018, 1-12.
L. Vi*, G.S. Baht*, E.J. Soderblom, H. Whetstone, Q. Wei, B. Furman, V. Puviindran, M. Foster, R. Poon, J.P. White, Y. Yahara, A. Ng, T. Barrientos, M. Grynpas, M.A. Mosely, B.A. Alman. Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice. Nature Communications. 9: 2018, 1-12.
G.S. Baht, L. Vi, B.A. Alman. The role of immune cells in fracture repair. Current Osteoporosis Reports. 16(2): 2018, 138-145.
G.S. Baht, L. Vi, B.A. Alman. The role of immune cells in fracture repair. Current Osteoporosis Reports. 16(2): 2018, 138-145.
C Xiong, Z Zhang, G.S. Baht*, N Terrando*. A mouse model of orthopedic surgery to study postoperative cognitive dysfunction and tissue regeneration. J Vis Exp. 27: 2018, 132.
C Xiong, Z Zhang, G.S. Baht*, N Terrando*. A mouse model of orthopedic surgery to study postoperative cognitive dysfunction and tissue regeneration. J Vis Exp. 27: 2018, 132.
G.S. Baht, P. Nadesan, David Silkstone, B.A. Alman. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 98: 2017, 31-36.
G.S. Baht, P. Nadesan, David Silkstone, B.A. Alman. Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair. Bone. 98: 2017, 31-36.
A.H. Ng*, G.S. Baht*, B.A. Alman, M.D. Grynpas. Bone marrow stress decreases osteogenic progenitors. Calcified Tissue International. 97: 2015, 476-86.
A.H. Ng*, G.S. Baht*, B.A. Alman, M.D. Grynpas. Bone marrow stress decreases osteogenic progenitors. Calcified Tissue International. 97: 2015, 476-86.
G.S. Baht, D. Silkstone, L. Vi, P. Nadesan, Y. Amani, H. Whetstone, Q. Wei, B.A. Alman. Exposure to a youthful circulation rejuvenates bone repair through modulation of β-catenin. Nature Communications. 6: 2015, 1-9.
G.S. Baht, D. Silkstone, L. Vi, P. Nadesan, Y. Amani, H. Whetstone, Q. Wei, B.A. Alman. Exposure to a youthful circulation rejuvenates bone repair through modulation of β-catenin. Nature Communications. 6: 2015, 1-9.
L. Vi, G.S. Baht, H. Whetstone, A. Ng, Q. Wei, R. Poon, S. Mylvaganam, M. Grynpas, B.A. Alman. Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis. Journal of Bone & Mineral Research. 30: 2015. 1090-1102.
L. Vi, G.S. Baht, H. Whetstone, A. Ng, Q. Wei, R. Poon, S. Mylvaganam, M. Grynpas, B.A. Alman. Macrophages promote osteoblastic differentiation in-vivo: implications in fracture repair and bone homeostasis. Journal of Bone & Mineral Research. 30: 2015. 1090-1102.
G.S. Baht, D. Silkstone, H. Whetstone, P. Nadesan, B.A. Alman. Activation of the hedgehog signaling pathway during fracture repair enhances osteoblast-dependent matrix formation. Journal of Orthopedic Research. 32: 2014. 581-586.
G.S. Baht, D. Silkstone, H. Whetstone, P. Nadesan, B.A. Alman. Activation of the hedgehog signaling pathway during fracture repair enhances osteoblast-dependent matrix formation. Journal of Orthopedic Research. 32: 2014. 581-586.
A.M. Craft, N. Ahmed, J.S. Rockel, G.S. Baht, B.A. Alman, R.A. Kandel, A.E. Grigoriadis, G.M. Keller. Specification of chondrocytes and cartilage formation from embryonic stem cell-derived paraxial mesoderm. Development. 140: 2013. 2597-2610.
A.M. Craft, N. Ahmed, J.S. Rockel, G.S. Baht, B.A. Alman, R.A. Kandel, A.E. Grigoriadis, G.M. Keller. Specification of chondrocytes and cartilage formation from embryonic stem cell-derived paraxial mesoderm. Development. 140: 2013. 2597-2610.
G.S. Baht, J. O’Young, A. Borovina, H. Chen, C.E. Tye, M. Karttunen, G. Lajoie, G.K. Hunter, H.A. Goldberg. Phosphorylation of Ser136 is required for potent bone sialoprotein-mediated nucleation of hydroxyapatite. Biochemical Journal. 428: 2010. 385–395.
G.S. Baht, J. O’Young, A. Borovina, H. Chen, C.E. Tye, M. Karttunen, G. Lajoie, G.K. Hunter, H.A. Goldberg. Phosphorylation of Ser136 is required for potent bone sialoprotein-mediated nucleation of hydroxyapatite. Biochemical Journal. 428: 2010. 385–395.
G.S. Baht, G.K. Hunter, H.A. Goldberg. Bone sialoprotein-collagen interaction promotes hydroxyapatite nucleation. Matrix Biology. 27: 2008. 600-608.
G.S. Baht, G.K. Hunter, H.A. Goldberg. Bone sialoprotein-collagen interaction promotes hydroxyapatite nucleation. Matrix Biology. 27: 2008. 600-608.
